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Omega-3 fatty acid prevents the development of heart failure by changing fatty acid composition in the heart

Sci Rep. 2020 Sep 23;10(1):15553. doi: 10.1038/s41598-020-72686-0. Haruhiro Toko, Hiroyuki Morita, Masanori Katakura, Michio Hashimoto, Toshiyuki Ko, Satoshi Bujo, Yusuke Adachi, Kazutaka Ueda, Haruka Murakami, Masato Ishizuka, Jiaxi Guo, Chunxia Zhao, Takayuki Fujiwara, Hironori Hara, Norifumi Takeda, Eiki Takimoto, Osamu Shido, Mutsuo Harada, Issei Komuro ...

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Enhanced nose-to-brain delivery of tranilast using liquid crystal formulations

Gerard Lee See, Florencio Arce Jr, Sabrina Dahlizar, Akie Okada, Muhammad Fikri Bin Mohd Fadli, Ichiro Hijikuro, Shoko Itakura, Masanori Katakura, Hiroaki Todo, Kenji Sugibayashi. Enhanced nose-to-brain delivery of tranilast using liquid crystal formulations. J Control Release. 2020;325:1-9. doi: 10.1016/j.jconrel.2020.06.028. ...

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Maternal dietary imbalance between omega-6 and omega-3 fatty acids triggers the offspring’s overeating in mice.

Maternal dietary imbalance between omega-6 and omega-3 fatty acids triggers the offspring’s overeating in mice.Sakayori N, Katakura M, Hamazaki K, Higuchi O, Fujii K, Fukabori R, Iguchi Y, Setogawa S, Takao K, Miyazawa T, Arita M, Kobayashi K.Commun Biol. 2020 Aug 28;3(1):473. doi: 10.1038/s42003-020-01209-4. ...

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多価不飽和脂肪酸と脳機能

多価不飽和脂肪酸と脳機能片倉賢紀Journal of Japanese Biochemical Society 92(5): 626-631 (2020) doi:10.14952/SEIKAGAKU.2020.920626 ...

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アラキドン酸が老齢ラットの認知機能に与える影響

Inoue, T., Hashimoto, M., Katakura, M., Hossain, S., Matsuzaki, K., Shido, O. Effect of chronic administration of arachidonic acid on the performance of learning and memory in aged rats.(2019) Food and Nutrition Research, 63, art. no. 1441. ...

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Theobromine improves working memory by activating the CaMKII/CREB/BDNF pathway in rats.

slam, R., Matsuzaki, K., Sumiyoshi, E., Hossain, M.E., Hashimoto, M., Katakura, M., Sugimoto, N., Shido, O. Theobromine improves working memory by activating the CaMKII/CREB/BDNF pathway in rats.(2019) Nutrients, 11 (4), art. no. 888. ...

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Heat attenuates sensitivity of mammalian cells to capsaicin.

Sugimoto, N., Matsuzaki, K., Katakura, M., Nakamura, H., Ueda, Y., Yachie, A., Shido, O. Heat attenuates sensitivity of mammalian cells to capsaicin.(2019) Journal of Biochemical and Molecular Toxicology, 33 (5), art. no. e22288. ...

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Chronic administration of theobromine inhibits mTOR signal in rats.

Sugimoto, N., Katakura, M., Matsuzaki, K., Sumiyoshi, E., Yachie, A., Shido, O. Chronic administration of theobromine inhibits mTOR signal in rats.(2019) Basic and Clinical Pharmacology and Toxicology, 124 (5), pp. 575-581. ...

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チョコレートでヒトの認知機能が増強される

Sumiyoshi, E., Matsuzaki, K., Sugimoto, N., Tanabe, Y., Hara, T., Katakura, M., Miyamoto, M., Mishima, S., Shido, O. Sub-chronic consumption of dark chocolate enhances cognitive function and releases nerve growth factors: A parallel-group randomized trial.(2019) Nutrients, 11 (11), art. no. 2800. ...

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慢性腎不全による認知機能の低下

Katakura, M. Elucidation of cognitive decline mechanism associated with the progression of chronic renal failure – involvement of neurogenesis inhibition.(2019) Impact, 2019 (7), pp. 41-43. ...

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Docosahexaenoic acid helps to lessen extinction memory in rats.

Hashimoto, M., Hossain, S., Katakura, M., Al Mamun, A., Shido, O. Docosahexaenoic acid helps to lessen extinction memory in rats. (2018) Molecules, 23 (2), art. no. 451. DOI: 10.3390/molecules23020451 ...

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Daily voluntary exercise enhances pilocarpine-induced saliva secretion and aquaporin 1 expression in rat submandibular glands.

Matsuzaki, K., Sugimoto, N., Katakura, M., Sumiyoshi, E., Hara, T., Hashimoto, M., Shido, O. Daily voluntary exercise enhances pilocarpine-induced saliva secretion and aquaporin 1 expression in rat submandibular glands. (2018) FEBS Open Bio, 8 (1), pp. 85-93. ...

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Neurogenesis in the thermoregulatory system.

Shido, O., Matsuzaki, K., Katakura, M. Neurogenesis in the thermoregulatory system. (2018) Handbook of Clinical Neurology. 156, pp457-463. ...

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ラットの肝臓における異なる炭素鎖長のペルオキシソームβ酸化による過フッ素化脂肪酸による誘導

Kudo, N., Bandai, N., Suzuki, E., Katakura, M., Kawashima, Y. Induction by perfluorinated fatty acids with different carbon chain length of peroxisomal β-oxidation in the liver of rats (2000) Chemico-Biological Interactions, 124 (2), pp. 119-132. ...

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Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice.

Yoneda, M., Sugimoto, N., Katakura, M., Matsuzaki, K., Tanigami, H., Yachie, A., Ohno-Shosaku, T., Shido, O. Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice. (2017) Journal of Nutritional Biochemistry, 39, pp. 110-116. ...

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Effect of dietary n-3 fatty acids supplementation on fatty acid metabolism in atorvastatin-administered SHR.Cg-Leprcp/NDmcr rats, a metabolic syndrome model.

Al Mamun, A., Hashimoto, M., Katakura, M., Tanabe, Y., Tsuchikura, S., Hossain, S., Shido, O. Effect of dietary n-3 fatty acids supplementation on fatty acid metabolism in atorvastatin-administered SHR.Cg-Leprcp/NDmcr rats, a metabolic syndrome model. (2017) Biomedicine and Pharmacotherapy, 85, pp. 372-379. ...

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Beneficial effects of dietary docosahexaenoic acid intervention on cognitive function and mental health of the oldest elderly in Japanese care facilities and nursing homes.

Hashimoto, M., Kato, S., Tanabe, Y., Katakura, M., Mamun, A.A., Ohno, M., Hossain, S., Onoda, K., Yamaguchi, S., Shido, O. Beneficial effects of dietary docosahexaenoic acid intervention on cognitive function and mental health of the oldest elderly in Japanese care facilities and nursing homes. (2017) Geriatrics and Gerontology International, 17 (2), pp. 330-337. ...

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Capsaicin partially mimics heat in mouse fibroblast cells in vitro.

ugimoto, N., Katakura, M., Matsuzaki, K., Nakamura, H., Yachie, A., Shido, O. Capsaicin partially mimics heat in mouse fibroblast cells in vitro. (2017) Naunyn-Schmiedeberg’s Archives of Pharmacology, 390 (3), pp. 281-289. ...

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Neural progenitor cell proliferation in the hypothalamus is involved in acquired heat tolerance in long-term heat-acclimated rats.

Matsuzaki, K., Katakura, M., Sugimoto, N., Hara, T., Hashimoto, M., Shido, O. Neural progenitor cell proliferation in the hypothalamus is involved in acquired heat tolerance in long-term heat-acclimated rats. (2017) PLoS ONE, 12 (6), art. no. e0178787. ...

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Direct exposure to mild heat promotes proliferation and neuronal differentiation of neural stem/progenitor cells in vitro.

Hossain, M.E., Matsuzaki, K., Katakura, M., Sugimoto, N., Mamun, A.A., Islam, R., Hashimoto, M., Shido, O. Direct exposure to mild heat promotes proliferation and neuronal differentiation of neural stem/progenitor cells in vitro. (2017) PLoS ONE, 12 (12), art. no. e0190356. ...